LairdLab.org
Welcome to the website of Angela R. Laird. My research focuses on systems modeling of functional neuroimaging data through the development of meta-analysis tools, functional ontologies, and connectivity methods.
Contact
Dr. Angela R. Laird, Ph.D.
Assistant Professor
Research Imaging Center
UT Health Science Center
7703 Floyd Curl Drive
San Antonio, Texas
78229-3900
lairda@uthscsa.edu
Phone: 210-567-8136
Fax: 210-567-8152
Meta-Analysis in Cognitive Neuroimaging
Dr. Laird serves as instructor for a graduate course, “Meta-Analysis in Cognitive Neuroimaging”, that is cross-listed as an interdisciplinary course at UTHSCSA (INTD 5046) and in the biology and psychology departments at UTSA (BIO 6973 and PSY 6973).
In this course, students are guided in choosing a meta-analysis topic, searching PubMed to find the relevant literature, coding the papers into the BrainMap database, and performing an ALE meta-analysis of the coordinate results. At the end of the semester, students give an oral presentation of their results and write a term paper written in traditional scientific format. One of these previous student meta-analyses was deemed appropriate for publication (Petacchi et al., 2005).
This course gives first- or second-year graduate students an introduction into the basics of functional neuroimaging and an opportunity to experience research first-hand without undergoing the difficulties inherent in teaching data acquisition and analysis of experiments to novice students.
Required Reading
- Fox PT, Parsons LM, Lancaster JL. Beyond the single study: Function-location meta-analysis in cognitive neuroimaging. Curr Opin Neurobiol 8, 178-187, 1998. [pdf] [PubMed]
- Turkeltaub PE, Eden GF, Zeffiro TA. Meta-analysis of the functional neuroanatomy of single word reading: Method and validation. Neuroimage 16, 765-780, 2002.[pdf] [PubMed]
- Laird AR, Fox M, Price CJ, Glahn DC, Uecker AM, Lancaster JL, Turkeltaub PE, Kochunov P, Fox PT. ALE meta-analysis: Controlling the false discovery rate and performing statistical contrasts. Hum Brain Mapp 25, 155-164, 2005. [pdf] [PubMed]
- BrainMap Scriber Users' Manual. [pdf]
Required Software
- Scribe [download] - database submission
- Sleuth [download] - creation of meta-analysis workspaces
- GingerALE [download] - performs ALE meta-analysis
- Mango [download] - image viewing
Previous Lectures
- Introduction to Quantitive Meta-Analysis: An Emerging Tool Set for Modeling Human Neural Systems [pdf]
- Cognitive Neuroscience: The Biology of the Mind [pdf]
- Mapping and Modeling Human Neural Systems with Modern Neuroimaging [pdf]
- Experimental Designs and Classic Experiments [pdf]
- Spatial Normalization of 3-D Human Brain Images[pdf]
- Basics of Statistical Modeling in Human Neuroimaging Experimentation [pdf]
- Meta-Analysis of Functional Neuroimaging Research [pdf]